In vivo magnetic resonance spectroscopy (MRS) is a powerful radiological technique that can noninvasively detect and quantify chemical concentrations in living tissue. The Mikkelsen Lab works to further the utility of MRS for modern biomedical science and the benefit of human health.
PI Dr. Mikkelsen's research achievements include being the project lead on the Big GABA project. This multi-site study gathered 26 research institutions to collect a large normative dataset of GABA-edited MRS data. It remains the largest sample of MRS data collected from healthy volunteers. Notable publications can be found here, here, and here. Others include advances in data processing algorithms to improve MRS data quality (ref, ref) and efforts to standardize the organization of MRS data and metadata (ref).
At Weill Cornell Medicine, Dr. Mikkelsen and his team are involved in several projects, as linked below.
